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Trypsin Inhibitors References

CAS:
9035-81-1
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Abrahamson, M. , Barrett, A. , Salvesen, G. and Grubb, A.
Isolation of Six Cysteine Proteinase Inhibitors from Human Urine. Their Physicochemical and Enzyme Kinetic Properties and Concentrations in Biological Fluids ,
J Biol Chem
 261 , 11282 , 1986
Acher, R. , Chauvet, J. , Arnon, R. and Sela, M.
Preparation and Properties of Poly-DL-Alanyl Derivatives of a Trypsin Inhibitor Kunits and Northrop Inhibitor. French ,
Eur J Biochem
 3 , 476 , 1968
Amir, D. and Haas, E.
Estimation of Intramolecular Distance Distributions in Bovine Pancreatic Trypsin Inhibitor by Site-Specific Labeling and Nonradiative Excitative Energy-Transfer Measurements ,
Biochemistry
 26 , 2162 , 1987
Andrews, A.
A New Approach to the General Detection and Measurement of Proteinase and Proteinase-Inhibitor Activities ,
Biochim Biophys Acta
 708 , 194 , 1982
Angliker, H. , Wikstrom, P. , Rauber, P. and Shaw, F.
The Synthesis of Lysylfluoromethanes and Their Properties as Inhibitors of Trypsin, Plasmin and Cathepsin B ,
Biochem J
 241 , 871 , 1987
Barnhill, M. and Trowbridge, C.
Reaction Heat Variation with pH in Formation of the Trypsin-Soybean Inhibitor Complex ,
J Biol Chem
 250 , 5501 , 1975
Beeley, J.
Ovomucoid Heterogeneity Examined by Flat Bed Isoelectric Focusing ,
Biochim Biophys Acta
 230 , 595 , 1971
Beeley, J. and Jevons, F.
Heterogeneity of Ovomucoid ,
Biochim Biophys Acta
 101 , 133 , 1965
Beeley, J. and McCairns, E.
Selective Isolation of Ovomucoid Using an Insolubilized Trypsin Derivative ,
Biochim Biophys Acta
 271 , 193 , 1972
Beeley, J.
Cyanogen Bromide Cleavage of Ovomucoid ,
Biochem J
 128 , 119P , 1972
Bidlingmeyer,V. , Leary, T. and Laskowski, M.
Identity of the Tryptic and alpha-Chymotryptic Reactive Sites on Soybean Trypsin Inhibitor (Kunitz) ,
Biochemistry
 11 , 3303 , 1972
Bier, M. , Terminiello, L. , Kuke, J. , Gibb, R. and Nord, F.
Investigations on Proteins and Polymers. X. Composition and Fractionation of Ovomucoid ,
Arch Biochem Biophys
 47 , 465 , 1953
Bieth, J. , Tourbez-Perrin, M. and Pochon, F.
Inhibition of alpha2-macro-globulin-bound Trypsin by Soybean Trypsin Inhibitor ,
J Biol Chem
 256 , 7954 , 1981
Birk, Y. , Gertler, A. and Khalef, S.
Further Evidence for a Dual, Independent Activity Against Trypsin and alpha-Chymotrypsin of Inhibitor AA from Soybeans ,
Biochim Biophys Acta
 147 , 402 , 1967
Blow, D. , Wright, C. , Kukla, D. , Ruhlmann, A. , Steigemann, W. and Huber, R.
A Model for the Association of Bovine Pancreatic Trypsin Inhibitor with Chymotrypsin and Trypsin ,
J Mol Biol
 69 , 137 , 1972
Bode, W. , Epp, O. , Huber, R. , Laskowski, M. and Ardelt, W.
The Crystal and Molecular Structure of the Third Domain of Silver Pheasant Ovomucoid ,
Eur J Biochem
 147 , 387 , 1985
Bosterling, B. and Quast, U.
Soybean Trypsin Inhibitor (Kunitz) is Doubleheaded. Kinetics of the Interaction of alpha-Chymotrypsin with Each Side ,
Biochim Biophys Acta
 657 , 58 , 1981
Boswell, D. , Jeppsson, J. , Brennan, S. and Carrell, R.
The Reactive Site of alpha-1-Antitrypsin is C-Terminal, Not N-Terminal ,
Biochim Biophys Acta
 744 , 212 , 1983
Brandt, P. and Woodward, C.
Hydrogen Exchange Kinetics of Bovine Pancreatic Trypsin Inhibitor-Sheet Protons in Trypsin-Bovine Pancreatic Trypsin Inhibitor, and Trypsinogen-Bovine Pancreatic Trypsin Inhibitor, and Trypsinogen-Isoleucylvaline-Bovine Pancreatic Trypsin Inhibitor ,
Biochemistry
 26 , 3156 , 1987
Chauvet, J. and Archer, R.
The Reactive Sites of Kunitz Bovine-Trypsin Inhibitor. Role of Lysine-15 in the Interaction with Chymotrypsin ,
Eur J Biochem
 54 , 31 , 1975
Chauvet, J. and Archer, R.
Isolation of a Trypsin Inhibitor (Kunitz Inhibitor) from Bovine Ovary by Affinity Chromatography Through Trypsin-Sepharose ,
F.E.B.S. Lett.
 23 , 317 , 1972
Chou, K. , Nemethy, G. , Pottle, M. and Scheraga, H.
Folding of the Twisted beta-Sheet in Bovine Pancreatic Trypsin Inhibitor ,
Biochemistry
 24 , 7948 , 1985
Chung, C. , Ives, H. , Almeda, S. and Goldberg, A.
Purification from Escherichia coli of a Periplasmic Protein that is a Potent Inhibitor of Pancreatic Proteases ,
J Biol Chem
 258 , 11032 , 1983
Cole, F. and Parthasarathy, R.
The Trypsin-Inhibitor Complex: Crystallization, Unit Cells and Space Groups ,
J Mol Biol
 71 , 105 , 1972
Creighton, T. and Goldenberg, D.
Kinetic Role of a Meta-stable Native-like Two-disulphide Species in the Folding Transition of Bovine Pancreatic Trypsin Inhibitor ,
J Mol Biol
 179 , 479 , 1984
Creighton, T.
Homology of Protein Structures: Proteinase Inhibitors ,
Nature
 255 , 743 , 1975
Davis, J. , Mapes, C. and Donovan, J.
Batch Purification of Ovomucoid and Characterization of the Purified Product ,
Biochemistry
 10 , 39 , 1971
DeLarco, J. and Liener, I.
The Involvement of an Arginine Residue of Trypsin in Its Interaction with the Kunitz Soybean Trypsin Inhibitor ,
Biochim Biophys Acta
 303 , 274 , 1973
Desai, U. , Osterhout, J. and Klibanov, A.
Protein Structure in the Lyophilized State: A Hydrogen Isotope Exchange/NMR Study with Bovine Pancreatic-Trypsin Inhibitor ,
J Am Chem Soc
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Donovan, J. and Beardslee, R.
Heat Stabilization Produced by Protein-Protein Association ,
J Biol Chem
 250 , 1966 , 1975
Donovan, J.
A Spectrophotometric and Spectrofluorometric Study of Intramolecular Interactions of Phenolic Groups in Ovomucoid ,
Biochemistry
 6 , 3918 , 1967
Ellis, L. , Bloomfield, V. and Woodward, C.
Hydrogen-Tritium Exchange Kinetics of Soybean Trypsin Inhibitor (Kunitz). Solvent Accessibility in the Folded Conformation ,
Biochemistry
 14 , 3413 , 1975
Empie, M. and Laskowski, M.
Thermodynamics and Kinetics of Single Residue Replacements in Avian Ovomucoid Third Domains: Effect of Inhibitor Interactions with Serine Proteinases ,
Biochemistry
 21 , 2274 , 1982
Engel, J. , Quast, U. , Heumann, H. , Krause, G. and Stefen, E.
Kinetic Studies of the Binding of Bovine Basic Pancreatic Trypsin Inhibitor to alpha-Chymotrypsin , Proteinase Inhibitors , H. Fritz, H. Tschesche, L. Greene, and E. Truscheit , Springer-Verlag, NY , 412 , 1974
Feeney, R. , Stevens, F. and Osuga, D.
The Specificities of Chicken Ovomucoid and Ovoinhibitor ,
J Biol Chem
 238 , 1415 , 1963
Feeney, R. , Osuga, D. and Maeda, H.
Heterogeneity of Avian Ovomucoids ,
Arch Biochem Biophys
 119 , 124 , 1967
Feinstein, G. and Gertler, A.
The Effect of Limited Proteolysis of Chicken Ovoinhibitor by Bovine Chymotrypsin on the Inhibitory Activities Against Trypsin, Chymotrypsin and Elastase ,
Eur J Biochem
 31 , 25 , 1972
Fex, G. , Grubb, A. , Loeffler, C. and Larsson, J.
Isolation and Partial Characterization of a Low Molecular Weight Trypsin Inhibitor from Human Urine ,
Biochim Biophys Acta
 667 , 303 , 1981
Figarella, C. , Negri, G. and Guy, O.
Studies on Inhibition of the Two Human Trypsins , Proteinase Inhibitors , H. Fritz, H. Tschesche, L. Greene, and E. Truscheit , Springer-Verlag, NY , 213 , 1974
Fink, E. and Greene, L.
Measurement of the Bovine Pancreatic Trypsin Inhibitors by Radioimmunoassay , Proteinase Inhibitors , H. Fritz, H. Tschesche, L. Greene, and E. Truscheit , Springer-Verlag, NY , 243 , 1974
Finkenstadt, W. and Laskowski, M.
Resynthesis by Trypsin of the Cleared Peptide Bond in Modified Soybean Trypsin Inhibitor ,
J Biol Chem
 242 , 771 , 1967
Finkenstadt, W. and Laskowski, M.
Peptide Bond Clearage on Trypsin-Trypsin Inhibitor Complex Formation ,
J Biol Chem
 240 , 962 , 1965
Fossum, K. and Whitaker, J.
Ficin and Papain Inhibitor from Chicken Egg White ,
Arch Biochem Biophys
 125 , 367 , 1968
Fraenkel-Conrat, H. , Bean, R. , Ducay, E. and Olcott, H.
Isolation and Characterization of Trypsin Inhibitor from Lima Beans ,
Arch Biochem Biophys
 37 , 393 , 1952
Fratalli, V. and Steiner, R.
Soybean Inhibitors. I. Separation and Some Properties of Three Inhibitors from Commercial Crude Soybean Trypsin Inhibitor ,
Biochemistry
 7 , 521 , 1968
Frattali, V. and Steiner, R.
Interaction of Trypsin and Chymotrypsin with a Soybean Proteinase Inhibitor ,
Biochem Biophys Res Commun
 34 , 480 , 1969
Frattali, V.
Soybean Inhibitors. III. Properties of a Low Molecular Weight Soybean Proteinase Inhibitor ,
J Biol Chem
 244 , 274 , 1969
Freed, R. and Ryan, D.
Isolation and Characterization of Genetic Variants of the Kunitz Soybean Trypsin Inhibitor ,
Biochim Biophys Acta
 624 , 562 , 1980
Gelin, B. and Karplus, M.
Sidechain Torsional Potentials and Motion of Amino Acids in Proteins: Bovine Pancreatic Trypsin Inhibitor ,
Proc Natl Acad Sci U S A
 72 , 2002 , 1975
Geratz, J. , Cheng, M. and Tidwell, R.
New Aromatic Diamidines with Central alpha-oxyalkane or alpha-W-Dioxyalkane Chains. Structure-Activity Relationships for the Inhibition of Trypsin, Pancreatic Kallikrein, and Thrombin and for the Inhibition of the Overall Coagulation Process ,
J Med Chem
 18 , 477 , 1975
Goldenberg, D. and Creighton, T.
Folding Pathway of a Circular Form of Bovine Pancreatic Trypsin Inhibitor ,
J Mol Biol
 179 , 527 , 1984
Harper, J. and Powers, J.
Reaction of Serine Proteases with Substituted 3-Alkoxy-7-amino-4-chloroisocoumarins: New Reactive Mechanism Based Inhibitors ,
Biochemistry
 24 , 7200 , 1985
Harper, J. , Hemmi, K. and Powers, J.
Reaction of Serine Proteases with Substituted Isocoumarins: Discovery of 3,4-Dichloroisocoumarin, a New General Mechanism Based Serine Protease Inhibitor ,
Biochemistry
 24 , 1831 , 1985
Haynes, R. and Feeney, R.
Fractionation and Properties of Trypsin and Chymotrypsin Inhibitors from Lima Beans ,
J Biol Chem
 242 , 5378 , 1967
Hixson, H. and Laskowski, M.
Formation from Trypsin and Modified Soybean Trypsin Inhibitor of a Complex Which Upon Kinetic Control Dissociation Yields Trypsin and Virgin Inhibitor ,
J Biol Chem
 245 , 2027 , 1970
Hixson, H. and Laskowski, M.
Evidence that Cocoonase and Trypsin Interact with Soybean Trypsin Inhibitor at the Same Reactive Site ,
Biochemistry
 9 , 166 , 1970
Hogle, J. and Liener, I.
Reduction and Reactivation of the Bowman-Birk Soybean Inhibitor ,
Can J Biochem
 51 , 1014 , 1973
Hvidt, A. and Pedersen, E.
A Comparative Study on the Basic Pancreatic Trypsin Inhibitor and Insulin by the Hydrogen-Exchange Method ,
Eur J Biochem
 48 , 333 , 1974
Ikenaka, T. , Tsunasawa, S. and Koide, T.
The Amino Acid Sequence of the Amino Terminal Region of Soybean Trypsin Inhibitor (Kunitz) ,
J. Biochem.
 69 , 251 , 1971
Ishida, M. , Hamaguchi, K. and Ikenaka, T.
A Study on the Interaction of Soybean Trypsin Inhibitor with Trypsin by Circular Dichroism ,
J. Biochem.
 67 , 363 , 1970
Jones, G. , Moore, S. and Stein, W.
Properties of Chromatographically Purified Trypsin Inhibitors from Lima Beans ,
Biochemistry
 2 , 66 , 1963
Karplus, S. , Snyder, G. and Sykes, B.
A Nuclear Magnetic Resonance Study of Bovine Pancreatic Trypsin Inhibitor. Tyrosine Titrations and Backbone NH Groups ,
Biochemistry
 12 , 1323 , 1973
Kato, I. , Schrode, J. , Kohr, W. and Laskowski, M.
Chicken Ovomucoid: Determination of Its Amino Acid Sequence, Determination of the Trypsin Reactive Site, and Preparation of all Three of Its Domains ,
Biochemistry
 26 , 193 , 1987
Kay, E.
Structure-Function Relationship of Proteinase Inhibitors from Soybean (Bowman-Birk) and Lima Bean ,
J Biol Chem
 254 , 7648 , 1979
Kobayashi, S. and Nagasawa, S.
Protease Inhibition in Guinea Pig Serum ,
Biochim Biophys Acta
 342 , 372 , 1974
Koide, T. and Ikenaka, T.
Studies on Soybean Trypsin Inhibitors. 3. Amino-Acid Sequence of the Carboxyl-Terminal Region and the Complete Amino-Acid Sequence of Soybean Trypsin Inhibitor ,
Eur J Biochem
 32 , 417 , 1973
Koide, T. , Ikenaka, T. , Ikeda, K. and Hamaguchi, K.
Studies on Soybean Trypsin Inhibitors. IX. Reconstitution of an Active Derivative from Two Inactive Fragments and the Contribution of Tryptophan-93 ,
J. Biochem.
 75 , 805 , 1974
Koide, T. , Tsunasawa, S. and Ikenaka, T.
Studies on Soybean Trypsin Inhibitors. 2. Amino Acid Sequence Around the Reactive Site of Soybean Trypsin Inhibitor (Kunitz) ,
Eur J Biochem
 32 , 408 , 1973
Koide, T. , Tsunasawa, S. and Ikenaka, T.
The Amino Acid Sequence of Soybean Trypsin Inhibitor (Kunitz) ,
J. Biochem.
 71 , 165 , 1972
Kosen, P. , Scheek, R. , Naderi, H. , Basus, V. , Manogaran, S. , Schmidt, P. , Oppenheimer, N. and Kuntz, I.
Two Dimensional 1H NMR of Three Spin-labeled Derivatives of Bovine Pancreatic Trypsin Inhibitor ,
Biochemistry
 25 , 2356 , 1986
Kosen, P. , Creighton, T. and Blout, E.
Circular Dichroism Spectroscopy of the Intermediates that Precede the Rate-Limiting Step of the Refolding Pathway of Bovine Pancreatic Trypsin Inhibitor. Relationship of Conformation and the Refolding Pathway ,
Biochemistry
 22 , 2433 , 1983
Koyama, S. , Kobayashi, Y. , Norioka, S. , Kyogoku, Y. and Ikenaka, T.
Conformational Studies by 1H Nuclear Magnetic Resonance of the Trypsin-Chymotrypsin B-III from Peanuts and Its Enzymatically Modified Derivative ,
Biochemistry
 25 , 8076 , 1986
Krahn, J. and Stevens, F.
Antitryptic Site of Lima Bean Protease Inhibitor ,
Biochemistry
 11 , 1804 , 1972
Krahn, J. and Stevens, F.
Lima Bean Protease Inhibitor: Comparative Study of the Trypsin and Chymotrypsin Inhibitor Activities of Four Chromatographically Pure Variants ,
F.E.B.S. Lett.
 28 , 313 , 1972
Krahn, J. and Stevens, F.
Peptide-Bond Hydrolysis Equilibria in the Antitrypsin Site of Lima Bean Protease Inhibitor ,
Biochemistry
 12 , 1330 , 1973
Krahn, J. and Stevens, F.
Stoichiometry of the Interaction of Lima Bean Protease Inhibitor with Trypsin and/or Chymotrypsin ,
F.E.B.S. Lett.
 13 , 339 , 1971
Krahn, J. and Stevens, F.
Lima Bean Trypsin Inhibitor. Limited Proteolysis by Trypsin and Chymotrypsin ,
Biochemistry
 9 , 2646 , 1970
Kunitz, M.
Crystalline Soybean Trypsin Inhibitor, II. General Properties ,
J Gen Physiol
 30 , 291 , 1947
Kunitz, M.
Isolation of a Crystalline Protein Compound of Trypsin and of Soybean Trypsin Inhibitor ,
J Gen Physiol
 30 , 311 , 1947
Kunitz, M.
Crystallization of a Trypsin Inhibitor from Soybean ,
Science
 101 , 668 , 1945
Laine, A. and Hayem, A.
Purification and Characterization of alpha-1-Antichymotrypsin from Human Pleural Fluid and Human Serum ,
Biochim Biophys Acta
 668 , 429 , 1981
Laskowski, M. , Kato, I. , Ardelt, W. , Cook, J. , Denton, A. , Empie, M. , Kohr, W. , Park, S. , Parks, K. , Schatzley, B. , Schoenberger, O. , Tashiro, M. , Vichot, G. , Whatley, H. , Wieczorek, A. and Wieczorek, M.
Ovomucoid Third Domains from 100 Avian Species: Isolation, Sequences, and Hypervariability of Enzyme-Inhibitor Contact Residues ,
Biochemistry
 26 , 202 , 1987
Lewis, J. and Ferguson, J.
The Inhibition of Fibrinolysin by Lima Bean Inhibitor ,
J Biol Chem
 204 , 503 , 1953
Liener, I.
The Intraperitoneal Toxicity of Concentrates of the Soybean Trypsin Inhibitor ,
J Biol Chem
 193 , 183 , 1951
Lievaart, P. and Stevenson, K.
The Isolation of Trypsin and Elastase from Moose Pancreas (Alces alces) by Affinity Chromatography on Lima-Bean Inhibitor-Sepharose Resin ,
Can J Biochem
 52 , 637 , 1974
Lineweaver, H. and Murray, C.
Identification of the Trypsin Inhibitor of Egg White with Ovomucoid ,
J Biol Chem
 171 , 565 , 1947
Liu, W. , Means, G. and Feeney, R.
The Inhibitory Properties of Avian Ovoinhibitors Against Proteolytic Enzymes ,
Biochim Biophys Acta
 229 , 176 , 1971
Liu, W. , Feinstein, G. , Osuga, D. , Haynes, R. and Feeney, R.
Modification of Arginines in Trypsin Inhibitors by 1,2-Cyclohexadione ,
Biochemistry
 7 , 2886 , 1968
Lunn, C. , Pak, P. , Van Savage, J. and Pigiet, V.
The Catalytic Active Site of Thioredoxin: Conformation and Homology with Bovine Pancreatic Trypsin Inhibitor ,
Biochim Biophys Acta
 871 , 257 , 1986
Luthy, J. , Praissman, M. , Finkenstadt, W. and Laskowski, M.
Detailed Mechanism of Interaction of Bovine beta-Trypsin with Soybean Trypsin Inhibitor (Kunitz). I. Stopped Flow Measurements ,
J Biol Chem
 248 , 1760 , 1973
Makhatadze, G. , Kim, K. , Woodward, C. and Privalov, P.
Thermodynamics of BPTI folding ,
Protein Sci
 2 , 2028 , 1993
Malthouse, J. , Primrose, W. , Mackenzie, N. and Scott, A.
13C NMR Study of the Ionizations within a Trypsin-Chloromethyl Ketone Inhibitor Complex ,
Biochemistry
 24 , 3478 , 1985
March, K. , Maskalick, D. , England, R. , Friend, S. and Gurd, F.
Analysis of Electrostatic Interactions and Their Relationship to Conformation and Stability of Bovine Pancreatic Trypsin Inhibitor ,
Biochemistry
 21 , 5241 , 1982
Markley, J.
Nuclear Magnetic Resonance Studies of Trypsin Inhibitors. Histidines of Virgin and Modified Soybean Trypsin Inhibitor (Kunitz) ,
Biochemistry
 12 , 2245 , 1973
Marks, C. , Naderi, H. , Kosen, P. , Kuntz, I. and Anderson, S.
Mutants of Bovine Pancreatic Trypsin Inhibitor Lacking Cysteines 14 and 38 Can Fold Properly ,
Science
 235 , 1370 , 1987
Marks, C. , Vasser, M. , Ng, P. , Henzel, W. and Anderson, S.
Production of Native, Correctly Folded Bovine Pancreatic Trypsin Inhibitor by Escherichia coli ,
J Biol Chem
 261 , 7115 , 1986
Martin, C. and Ventura, M.
Trypsin and Chymotrypsin Inhibitor of Vigna unguiculata Seeds. Involvement of Tyrosyls in Its Interaction with Proteases ,
An Acad Bras Cienc
 58 , 297 , 1986
Martodam, R. and Liener, I.
The Interaction of alpha-Antitrypsin with Trypsin, Chymotrypsin and Human Leukocyte Elastase as Revealed by End Group Analysis ,
Biochim Biophys Acta
 667 , 328 , 1981
Masson, A. and Wuthrich, K.
Proton Magnetic Resonance Investigation of the Conformation Properties of the Basic Pancreatic Trypsin Inhibitor ,
F.E.B.S. Lett.
 31 , 114 , 1973
Matsuda, T. , Watanabe, K. and Nakamura, R.
Immunochemical Studies on Thermal Denaturation of Ovomucoid ,
Biochim Biophys Acta
 707 , 121 , 1982
Matsushima, K.
An Undescribed Trypsin Inhibitor in Egg White ,
Science
 127 , 1178 , 1958
Mattis, J. and Laskowski, M.
pH Dependence of the Equilibrium Constant for the Hydrolysis of the Arg 63-Ile Reactive-Site Peptide Bond in Soybean Trypsin Inhibitor (Kunitz) ,
Biochemistry
 12 , 2239 , 1973
Melamed, M.
Electrophoretic Properties of Ovomucoid ,
Biochem J
 103 , 895 , 1967
Menegatti, E. , Bartolotti, F. , Minchiotti, L. and De Marco, A.
Isolation and Characterization of a New Form of the Porcine Pancreatic Secretory Trypsin Inhibitor. Biochemical Studies and High-Resolution 1H-NMR ,
Biochim Biophys Acta
 707 , 50 , 1982
Millar, D. , Willick, G. , Steiner, R. and Fratalli, V.
Soybean Inhibitors. IV. The Reversible Self-Association of a Soybean Proteinase Inhibitor ,
J Biol Chem
 244 , 281 , 1969
Murthy, G. , Gilardeau, C. and Chetien, M.
Partial Sequence of Trypsin Inhibitor from Ovomucoid ,
Can J Biochem
 51 , 1548 , 1973
Muszkat, K. , Weinstein, S. , Khait, I. and Vered, M.
Effects of Proteinase-Inhibitor Binding on Accessibility of Exposed Tyrosines: A Photochemically Induced Dynamic Nuclear Polarization Study of Bovine Pancreatic Trypsin Inhibitor Complexes with Trypsin, Chymotrypsin and Their Zymogens ,
Biochemistry
 21 , 3775 , 1982
Nanninga, L. and Guest, M.
On the Interaction of Fibrinolysin (Plasmin) with Inhibitors Antifibrinolysin and Soybean Trypsin Inhibitor ,
Arch Biochem Biophys
 108 , 542 , 1964
Niekamp, C. , Hixson, H. and Laskowski, M.
Peptide Bond Hydrolysis Equilibria in Native Proteins. Conversion of Virgin into Modified Soybean Trypsin Inhibitor ,
Biochemistry
 8 , 16 , 1969
Nishino, N. and Izumiya, N.
Anti-Tryptic Activity of a Synthetic Bicyclic Fragment of Soybean Bowman-Birk Inhibitor ,
Biochim Biophys Acta
 708 , 233 , 1982
N‡ray-Szabo, G. and Nagy, P.
Electrostatic Lock-and-Key Model for the Study of Biological Isosterism: Role of Structural Water in the Binding of Basic Pancreatic Trypsin Inhibitor to beta-Trypsin ,
Enzyme
 36 , 44 , 1986
Odani, S. , Koide, T. and Ikenaka, T.
Studies on Soybean Trypsin Inhibitor. II. Accidentally Modified Kunitz Soybean Trypsin Inhibitor ,
J. Biochem.
 70 , 925 , 1971
Ohlsson, B. , Westrom, B. and Karlsson, B.
In Vitro Interaction of Porcine Serum and Colostrum Protease Inhibitors with Pancreatic Trypsin, Chymotrypsin and Elastase ,
Biochim Biophys Acta
 705 , 357 , 1982
Papainaonnou, S. and Liener, I.
The Involvement of Tyrosyl and Amino Groups in the Interaction of Trypsin and a Soybean Trypsin Inhibitor ,
J Biol Chem
 245 , 4931 , 1970
Pershina, L. and Hvidt, A.
A Study by the Hydrogen Exchange Method of the Complex Formed Between the Basic Pancreatic Trypsin Inhibitor and Trypsin ,
Eur J Biochem
 48 , 339 , 1974
Primrose, W. , Scott, A. , Mackenzie, N. and Malthouse, J.
A 13C-NMR Investigation of Ionizations with a Trypsin-Inhibitor Complex. Evidence that the pKa of Histidine-57 is Raised by interaction with the Hemikelal Oxyanion ,
Biochem J
 231 , 677 , 1985
Pubols, M. , Bartelt, D. and Greene, L.
Trypsin Inhibitor from Human Pancreas and Pancreatic Juice ,
J Biol Chem
 249 , 2235 , 1974
Pusztai, A. , Grant, G. , Stewart, J. and Watt, W.
Isolation of Soybean Trypsin Inhibitors by Affinity Chromatography on Anhydrotrypsin-Sepharose 4B ,
Anal Biochem
 172 , 108 , 1988
Quast, U. , Engel, J. , Steffen, E. , Maiar, G. , Tschesche, H. and Jering, H.
Kinetics of Binding of Bovine Trypsin-Kallikrein Inhibitor (Kunitz) in Which the Reactive-Site Peptide Bond Lys-15-Ala-16 is Cleaved to alpha-Chymotrypsin and beta-Trypsin ,
Eur J Biochem
 52 , 505 , 1975
Quast, U. , Engel, J. , Steffen, E. , Tschesche, H. and Kupfer, S.
Stopped Flow Kinetics of Resynthesis of the Reactive Site Peptide Bond in Kallikrein Inhibitor (Kunitz) by beta-Trypsin ,
Biochemistry
 17 , 1675 , 1978
Quast, U. , Engel, J. , Steffen, E. , Tschesche, H. , Jering, H. and Kupfer, S.
The Effect of Cleaving the Reactive-Site Peptide Bond Lys-15-Ala-16 on the Conformation of Bovine Trypsin-Kallikrein Inhibitor (Kunitz) as Revealed by Solvent-Perturbation Spectra, Circular Dichroism and Fluorescence ,
Eur J Biochem
 52 , 511 , 1975
Quast, U. , Engel, J. , Heumann, H. , Krause, G. and Steffen, E.
Kineticsof the Interaction of Bovine Pancreatic Trypsin Inhibitor (Kunitz) with alpha-Chymotrypsin ,
Biochemistry
 13 , 2512 , 1974
Rackis, J. and Anderson, R.
Isolation of Four Soybean Trypsin Inhibitors by DEAE-Cellulose Chromatography ,
Biochem Biophys Res Commun
 15 , 230 , 1964
Ray, A. , Guha, M. and Sinha, N.
Purification and Characterization of an Acidic Trypsin/Subtilisin Inhibitor from Tortoise Egg White ,
Biochim Biophys Acta
 716 , 126 , 1982
Reddy, K. and Markus, G.
Further Evidence for an Active Center in Streptokinase-Plasminogen Complex: Interaction with Pancreatic Trypsin Inhibitor ,
Biochem Biophys Res Commun
 51 , 672 , 1973
Rhodes, M. , Bennett, N. and Feeney, R.
The Trypsin and Chymotrypsin Inhibitors from Avian Egg Whites ,
J Biol Chem
 235 , 1686 , 1960
Richardson, M. , Campos, F. , Xavier-Filho, J. , Macedo, M. , Maia, G. and Yarwood, A.
The Amino Acid Sequence and Reactive (Inhibitory) Site of the Major Trypsin Isoinhibitor (DE5) Isolated from Seeds of the Brazilian Carolina Tree (Adenanthera pavonina L.) ,
Biochim Biophys Acta
 872 , 134 , 1986
Roder, H. , Wagner, G. and Wuthrich, K.
Amide Proton Exchange in Proteins by EX1 Kinetics: Studies of the Basic Pancreatic Trypsin Inhibitor at Variable pH and Temperature ,
Biochemistry
 24 , 7396 , 1985
Roder, H. , Wagner, G. and Wuthrich, K.
Individual Amide Proton Exchange Rates in Thermally Unfolded Basic Pancreatic Trypsin Inhibitor ,
Biochemistry
 24 , 7407 , 1985
Roll, D. and Glew, R.
Isolation and Characterization of Rat alpha-1-Antitrypsin ,
J Biol Chem
 256 , 8190 , 1981
Sanderson, J. , Freed, R. and Ryan, D.
Thermal Denaturation of Genetic Variants of the Kunitz Soybean Trypsin Inhibitor ,
Biochim Biophys Acta
 701 , 237 , 1982
Schwarz, H. , Hinz, H. , Mehlich, A. , Tschesche, H. and Wenzel, H.
Stability Studies on Derivatives of the Bovine Pancreatic Trypsin Inhibitor ,
Biochemistry
 26 , 3544 , 1987
Schweitz, H. , Vincent, J. and Lazdunski, M.
Trypsin-Pancreatic Secretory Inhibitor-(Kazal Inhibitor) Interaction. Kinetic and Thermodynamic Properties ,
Biochemistry
 12 , 2841 , 1973
Sealock, R. and Laskowski, M.
Thermodynamics and Kinetics of the Reactive Site Peptide-Bond Hydrolysis in Bovine Pancreatic Secretory Trypsin Inhibitor (Kazal) ,
Biochemistry
 12 , 3139 , 1973
Seidl, D. and Liener, I.
Isolation and Properties of Complexes of the Bowman-Birk Soybean Inhibitor with Trypsin and Chymotrypsin ,
J Biol Chem
 247 , 3533 , 1972
Simon, I. , TŸchsen, E. and Woodward, C.
Effect of Trypsin Binding on the Hydrogen Exchange Kinetics of Bovine Pancreatic Trypsin Inhibitor beta-Sheet NH's ,
Biochemistry
 23 , 2064 , 1984
Smith, S. , Farr-Jones, S. , Griffin, R. and Bachovchin, W.
Crystal Versus Solution Structures of Enzymes: NMR Spectroscopy of a Crystalline Serine Protease ,
Science
 244 , 961 , 1989
Stearner, S. and Azuma, S.
Early Radiation Lethality: Enzyme Release and the Protective Action of Soybean Trypsin Inhibitor ,
Proc Soc Exp Biol Med
 128 , 913 , 1968
Steiner, R.
The Reduction and Reoxidation of the Disulfide Bonds of Soybean Trypsin Inhibitor ,
Biochim Biophys Acta
 100 , 111 , 1965
Steiner, R. and Frattali, V.
Purification and Properties of Soybean Protein Inhibitor of Proteolytic Enzymes ,
J Agric Food Chem
 17 , 513 , 1969
Steiner, R. , Lunasin, A. and Horan, C.
Specifically Located Fluorescent Probes: Properties of a Fluorescent Conjugate of Soybean Trypsin Inhibitor Containing Dansylamino-Tyrosine Groups ,
Biochim Biophys Acta
 336 , 407 , 1974
Steven, F. and Griffin, M.
Evidence for Exchange of Inhibitors Which Bind to The Active Site of Trypsin. Displacement of One Inhibitor with a Competitive Inhibitor ,
Biochim Biophys Acta
 662 , 190 , 1981
Stevens, F. and Doskoch, E.
Lima Bean Protease Inhibitor: Reduction and Reoxidation of the Disulfide Bonds and Their Reactivity in the Trypsin-Inhibitor Complex ,
Can J Biochem
 51 , 1021 , 1973
Summaria, L. , Leonida, A. , Bernabe, P. and Robbins, K.
The Activation of Plasminogen to Plasmin by Urokinase in the Presence of the Plasmin Inhibitor Trasylol ,
J Biol Chem
 250 , 3988 , 1975
Swaminathan, S. , Ichiye, T. , van Gunsteren, W. and Karplus, M.
Time Dependence of Atomic Fluctuations in Proteins: Analysis of Local and Collective Motions in Bovine Pancreatic Trypsin Inhibitor ,
Biochemistry
 21 , 5230 , 1982
Sweet, R. , Wright, H. , Janin, J. , Chothia, C. and Blow, D.
Crystal Structure of the Complex of Porcine Trypsin with Soybean Trypsin Inhibitor (Kunitz) at 2.6 Å Resolution ,
Biochemistry
 13 , 4212 , 1974
Takahari, H. , Okamoto, H. and Sugawara, K.
Specific Modification of the Functional Arginine Residue in Soybean Trypsin Inhibitor (Kunitz) by Peptidylarginine Deiminase ,
J Biol Chem
 260 , 8378 , 1985
Tan, C. and Stevens, F.
Amino Acid Sequence of Lima Bean Protease Inhibitor Component IV. I. Isolation and Sequence Determination of the Tryptic Peptides ,
Eur J Biochem
 18 , 503 , 1971
Tan, C. and Stevens, F.
Amino Acid Sequence of Lima Bean Protease Inhibitor Component IV. 2. Isolation and Sequence Determination of the Chymotryptic Peptides and the Complete Amino Acid Sequence ,
Eur J Biochem
 18 , 515 , 1971
Tanaka, Y. , Maehara, S. , Sumi, H. , Toki, N. , Moriyama, S. and Sasaki, K.
Purification and Partial Characterization of Two Forms of Urinary Trypsin Inhibitor ,
Biochim Biophys Acta
 705 , 192 , 1982
Temler, R. , Simon, E. and Amiguet, P.
Comparison of the Interactions of Soya Bean Protease Inhibitors with Rat Pancreatic Enzymes and Human Trypsin ,
Enzyme
 30 , 105 , 1983
Tomimatsu, Y. , Clary, J. and Barlulovich, J.
Physical Characterization of Ovoinhibitor, a Trypsin and Chymotrypsin Inhibitor from Chicken Egg White ,
Arch Biochem Biophys
 115 , 536 , 1966
Townshend, G. , Botes, D. and Visser, L.
Properties of Fragments Prepared from Bowman-Birk Inhibitor ,
Biochim Biophys Acta
 701 , 346 , 1982
Travis, J.
Human Pancreatic Enzymes: Interaction of Human Trypsin with Chicken Ovomucoid ,
Biochem Biophys Res Commun
 44 , 793 , 1971
Travis, J. and Salvesen, G.
Human Plasma Proteinase Inhibitors ,
Annu Rev Biochem
 52 , 655 , 1983
Tschesche, H. , Jering, H. , Schorp, G. and Dietl, T.
Reactive Site Cleavage, Thermodynamic Control Resynthesis, and Properties of Chemically Derivatized Trypsin-kallikrein-Inhibitors , Proteinase Inhibitors , H. Fritz, H. Tschesche, L. Greene, and E. Truscheit , Springer-Verlag, NY , 362 , 1974
Tuchsen, E. and Woodward, C.
Assignment of Asparagine-44 Side-Chain Primary Amide 1H NMR Resonances and the Peptide Amide N1H Resonance of Glycine-37 in Basic Pancreatic Trypsin Inhibitor ,
Biochemistry
 26 , 1918 , 1987
Vincent, J. , Peron-Renner, M. , Pudles, J. and Lazdunski, M.
The Association of Anhydrotrypsin with the Pancreatic Trypsin Inhibitors ,
Biochemistry
 13 , 4205 , 1974
Vincent, J. , Schweitz, H. and Lazdunski, M.
Guanidation of Lysine-15 in the Active Site of the Basic Pancreatic Trypsin Inhibitor. Implications for Complex Formation with Trypsin and Chymotrypsin ,
Eur J Biochem
 42 , 505 , 1974
Vincent, J. and Lazdunski, M.
Trypsin-Pancreatic Trypsin Inhibitor Association. Dynamics of the Interaction and Role of Disulfide Bridges ,
Biochemistry
 11 , 2967 , 1972
Wagner, G. and Brunwiler, D.
Toward the Complete Assignment of the Carbon Nuclear Magnetic Resonance Spectrum of the Basic Pancreatic Trypsin Inhibitor ,
Biochemistry
 25 , 5839 , 1986
Wagner, G. and WŸthrich, K.
Amide Proton Exchange and Surface Conformation of the Basic Pancreatic Trypsin Inhibitor in Solution. Studies with Two-dimensional Nuclear Magnetic Resonance ,
J Mol Biol
 160 , 343 , 1982
Wagner, G. and WŸthrich, K.
Sequential Resonance Assignments in Protein 1H Nuclear Resonance Spectra. Basic Pancreatic Trypsin Inhibitor ,
J Mol Biol
 155 , 347 , 1982
Waheed, A. and Salahuddin, A.
Hydrogen-Ion Titration Curve of Ovomucoid ,
Biochim Biophys Acta
 379 , 147 , 1975
Waheed, A. and Salahuddin, A.
Isolation and Characterization of a Variant of Ovomucoid ,
Biochem J
 147 , 139 , 1975
Wang, D. , Wu, K. and Feinman, R.
The Reaction of alpha-2-macroglobulin-bound Trypsin in Soybean Trypsin Inhibitor ,
J Biol Chem
 256 , 10934 , 1981
Wang, T. and Kassell, B.
The Preparation of a Chemically Cross-Linked Complex of the Basic Pancreatic Trypsin Inhibitor with Trypsin ,
Biochemistry
 13 , 698 , 1974
Watanabe, K. , Matsuda, T. and Sato, Y.
The Secondary Structure of Ovomucoid and Its Domain as Studied by Circular Dichroism ,
Biochim Biophys Acta
 667 , 242 , 1981
Wei, C.
Crystallization of Two Cubic Forms of Soybean Trypsin Inhibitor EI, a Member of the Bowman-Birk Inhibitor Family ,
J Biol Chem
 258 , 9357 , 1983
Westhaemper, R. and Abeles, R.
Novel Inactivators of Serine Proteases Based on 6-Chloro-2-pyrone ,
Biochemistry
 22 , 3256 , 1983
Westphal, M. , Hammonds, R. and Li, C.
Detection of Bovine Pancreatic Trypsin Inhibitor (bPTI) in Bovine and Ovine Pituitaries, Bovine Brain and Adrenal Medulla. A Specific Radioimmunoassay for beta-PTI ,
Arch Biochem Biophys
 229 , 555 , 1984
Wieczorek, M. and Laskowski, M.
Formation of Covalent Hybrids from Amino-Terminal and Carboxy-Terminal Fragments of Two Ovomucoid Third Domains ,
Biochemistry
 22 , 2630 , 1983
Wlodawer, A. , Nachman, J. , Gilliland, G. , Gallagher, W. and Woodward, C.
Structure of Form III Crystals of Bovine Pancreatic Trypsin Inhibitor ,
J Mol Biol
 198 , 469 , 1987
Wlodawer, A. , Walter, J. , Huber, R. and Sjšlin, L.
Structure of Bovine Pancreatic Trypsin Inhibitor ,
J Mol Biol
 180 , 301 , 1984
Woodward, C. and Ellis, L.
Hydrogen Exchange Kinetics Changes Upon Formation of the Soybean Trypsin-Inhibitor Complex ,
Biochemistry
 14 , 3419 , 1975
Wu, Y. and Scheraga, H.
Studies of Soybean Trypsin Inhibitor. I. Physicochemical Properties ,
Biochemistry
 1 , 698 , 1962
Wu, Y. and Scheraga, H.
Studies of Soybean Trypsin Inhibitor. II. Conformational Properties ,
Biochemistry
 1 , 905 , 1962
Yamamoto, M. and Ikenaka, T.
Studies on Soybean Trypsin Inhibitors. I. Purification and Characterization of Two Soybean Trypsin Inhibitors ,
J. Biochem.
 62 , 141 , 1967
Zahnley, J.
Evidence That the Two Binding Sites for Trypsin on Chicken Ovoinhibitor are not Equivalent. Dissociation of the Complexes with Porcine Trypsin ,
J Biol Chem
 249 , 4282 , 1974
Zahnley, J.
Independent Heat Stabilization of Proteases Associated with Multiheaded Inhibitors. Complexes of Chymotrypsin, Subtilisin and Trypsin with Chicken Ovoinhibitor and with Lima Bean Protease Inhibitor ,
Biochim Biophys Acta
 613 , 178 , 1980
Zahnley, J.
Independent Heat Stabilization of Proteases Associated with Multiheaded Inhibitors: Trypsin Bound at Nonequivalent Sites on Chicken Ovoinhibitor ,
J Biol Chem
 254 , 9721 , 1979

Trypsin Inhibitors Products

Description
Activity
Code
Cat. #
Size
Price
Description
Trypsin Inhibitor, Lima Bean, AF
Source:
Lima Bean
Animal Free/AF. Fraction III of the preparation described by Fraenkel-Conrat, et al., Arch. Biochem. Biophys., 37, 393 (1952). Supplied as a dialyzed, lyophilized powder.
Store at 2-8°C.
…
Activity
---
Code
LBI
LS002829
100 mg
$160.00
LS002830
1 gm
$1,150.00
LS002831
Bulk
---
The minimum amount for bulk packaging/pricing for this product is 20000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
Description
Trypsin Inhbitor, Ovomucoid
Source:
Egg White
Mucoprotein and antitryptic factor of egg white described by Lineweaver and Murray, J. Biol. Chem., 171, 565 (1947). A dialyzed, dried powder.
Store at 2-8°C.
…
Activity
---
Code
OI
LS003085
500 mg
$94.00
LS003087
1 gm
$160.00
LS003086
2 gm
$310.00
LS003089
Bulk
---
The minimum amount for bulk packaging/pricing for this product is 100000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
Description
Trypsin Inhibitor, Soybean, Purified, AF
Source:
Soybean
Chromatographically purified as described by Frattali, V., and Steiner, R.: Biochem., 7, 521 (1968), modified by Worthington. A dialyzed, lyophilized powder. Purity >90% checked using SDS PAGE.
Store at 2-8°C.
…
Activity
---
Code
SI
LS003570
100 mg
$80.00
LS003571
1 gm
$500.00
LS003573
Bulk
---
The minimum amount for bulk packaging/pricing for this product is 20000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
Description
Trypsin Inhibitor, Soybean, AF
Source:
Soybean
A partially purified lyophilized powder.
Store at 2-8°C.
…
Activity
---
Code
SIC
LS003589
10 gm
$700.00
LS003587
1 gm
$92.00
LS003590
Bulk
---
The minimum amount for bulk packaging/pricing for this product is 200000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
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