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Chymotrypsin References

Source:
Bovine Pancreas
CAS:
9004-07-3
EC:
3.4.21.1
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Abdullah, M. , Siddiqui, A. , Hill, J. and Davies, R.
The Purification of alpha-Antichymotrypsin from Human Serum Using DNA-Cellulose Chromatography ,
Arch Biochem Biophys
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Adelson, J. and Rothman, S.
Selective Pancreatic Enzyme Secretion Due to a New Peptide Called Chymodenin ,
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Adlercreutz, P. and Clapes, P.
Catalytic Properties of alpha-Chymotrypsin in Organic Media ,
Biomed Biochim Acta
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Ainslie, G. and Neet, K.
Cooperativity and the Slow Isomerization of delta-Chymotrypsin ,
Mol Cell Biochem
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Almond, H. and Niemann, C.
Transpeptidation and the alpha-Chymotrypsin-Catalyzed Hydrolysis of alpha-Amino Acid Esters, Hydroxamides, Amides and Hydrazides ,
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Benzamidomethaneborinic Acid: Synthesis and Inhibition of Chymotrypsin ,
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Amshey, J. and Bender, M.
Fluorine Magnetic Resonance Studies of Fluorine-Substituted Benzoyl Chymotrypsin ,
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The Deacylation of Substituted Benzoyl-alpha-Chymotrypsins ,
Arch Biochem Biophys
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Ando, M. , Gerig, J. and Luk, K.
Motion at the Active Site of [(4-Fluorophenyl)sulfonyl]Chymotrypsin ,
Biochemistry
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Antonov, V. and Rumsh, L.
Substrate Activation by Non-Covalent Binding in the Active Site of Chymotrypsin ,
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Applewhite, T. , Martin, R. and Niemann, C.
The alpha-Chymotrypsin-catalyzed Hydrolysis of Methyl Hippurate in Aqueous Solutions at 25°C and pH 7.9, Its Inhibition by Indole and its Dependence upon Added Non-Aqueous Solvents ,
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Resonance Raman Carbonyl Frequencies and Ultraviolet Absorption Maxima as Indicators of the Active Site Environment in Native and Unfolded Chromophoric Acyl-alpha-chymotrypsin ,
Biochemistry
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Asboth, B. and Polgar, L.
Transition-State Stabilization at the Oxyanion Binding Sites of Serine and Thiol Proteinases: Hydrolyses of Thiono and Oxygen Esters ,
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Biochemistry
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Babin, D. , Peanasky, R. and Goos, S.
The Isoinhibitors of Chymotrypsin/Elastase from Ascaris lumbricoides: The Primary Structure ,
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Baek, D. , Reed, P. , Daniels, S. and Katzenellenbogen, J.
Alternate Substrate Inhibitors of an alpha-Chymotrypsin: Enantioselective Interaction of Aryl-Substituted Enol Lactones ,
Biochemistry
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The Reaction of an alpha-Aza-Amino Acid Derivative with Chymotrypsin and Its Use as a Ligand for Covalent Affinity Purification ,
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Fluorometric Continuous Kinetic Assay of alpha-Chymotrypsin Using New Protease Substrates Possessing Long-Wave Excitation and Emission Maxima ,
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Bender, M. and Nakamura, K.
The Effect of Structure on the Rates of Some alpha-Chymotrypsin-catalyzed Reactions ,
J Am Chem Soc
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Bender, M. and Zerner, B.
The Formation of an Acylenzyme-Intermediate in the alpha-Chymotrypsin-catalyzed Hydrolyses of Nonlabile trans-Cinnamic Acid Esters ,
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Bender, M.
The Mechanism of alpha-Chymotrypsin-catalyzed Hydrolyses ,
J Am Chem Soc
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Benmouyal, P. and Trowbridge, C.
Spectroscopic Changes Accompanying Some Reactions of Trypsin and alpha-Chymotrypsin ,
Arch Biochem Biophys
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Berezin, I. , Varfolomeyev, S. and Martinek, K.
A Flash-Induced Reaction of a Synthetic Light-Sensitive Substrate with alpha - Chymotrypsin ,
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Specificity of alpha-Chymotrypsin ,
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Berliner, L. and Wong, S.
Spin-labeled Sulfonyl Fluorides as Active Site Probes of Protease Structure. I. Comparison of the Active Site Environments in alpha-Chymotrypsin and Trypsin ,
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Birk, Y.
Purification and Some Properties of a Highly Active Inhibitor of Trypsin and alpha-Chymotrypsin from Soybeans ,
Biochim Biophys Acta
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The Importance of the Conformation of the Tetrahedral Intermediate for the alpha-Chymotrypsin-Catalyzed Hydrolysis of Peptide Substances ,
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Blevins, R. and Tulinsky, A.
The Refinement and the Structure of the Dimer of alpha-Chymotrypsin at 1.67-Å Resolution ,
J Biol Chem
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Blevins, R. and Tulinsky, A.
Comparison of the Independent Solvent Structures of Dimeric alpha-Chymotrypsin with Themselves and with gamma-Chymotrypsin ,
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Energetics of alpha-Chymotrypsin-Mediated Hydrolysis of a Strained Cyclic Ester ,
Biochemistry
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Borovsky, D. and Schlein, Y.
Quantitative Determination of Trypsinlike and Chymotrypsinlike Enzymes in Insects ,
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Breaux, E. and Bender, M.
The Binding of Specific and Non-Specific Aldehyde Substrate Analogs to alpha-Chymotrypsin ,
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Brecher, A. , Moehlman, T. and Hann, W.
Utilization of Chymotrypsin as a Sole Carbon and (or) Nitrogen Source by Escherichia coli ,
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N-Terminal Amino Acid Sequence of Trypsinogen from the Lesser Rorqual Balaenoptera acutorostrata (Cetacea) ,
Biochim Biophys Acta
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Briges, A.J. and Knowles, J.R.
An Examination of the Utility of Photogenerated Reagents by Using alpha-Chymotrypsin ,
Biochem J
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Brinigar, W.S. and Chao, T.L.
Is the Serine Protease "Charge Relay System" a Charge Relay System? ,
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Brouwer, A.C. and Kirsch, J.F.
Investigation of Diffusion - Limited Rates of Chymotrypsin Reactions by Viscosity Variation ,
Biochemistry
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Kinetic Evidence for a Two-Step Mechanism for the Binding of Chymotrypsin to alpha-1-Proteinase Inhibitor ,
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A New Spectrophotometric Method for the Determination of Chymotrypsin Activity ,
Anal Biochem
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Solid-State NMR Assessment of Enzyme Active Center Structure Under Nonaqueous Conditions ,
J Biol Chem
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Carey, P.R. and Schneider, H.
Resonance Raman Spectra of Chymotrypsin Acyl Enzymes ,
Biochem Biophys Res Commun
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Carrere, J. , Figarella, C. , Guy, O. and Thouvenot, J.P.
Human Pancreatic Chymotrypsinogen A: A Non-competitive Enzyme Immuno Assay, and Molecular Forms in Serum and Amniotic Fluid ,
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Castenada-Agullo, M. and Del Castillo, L.
Effect of the Medium Dielectric Strength on the Activity of alpha-Chymotrypsin ,
J Gen Physiol
 43 , 127 , 1959
Castenada-Agullo, M. and Del Castillo, L.
The Action of alpha-Chymotrypsin Upon Mixtures of Esters and Proteins at Enzyme-Saturating Concentrations ,
J Gen Physiol
 42 , 49 , 1958
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The Fecal Chymotrypsin Photometric Assay in the Evaluation of Exocrine Pancreatic Capacity. Comparison with Other Direct and Indirect Pancreatic Function Tests ,
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Cerovsky, V. , Ullmann, D. and Jakubke, H.
S'-Subsite Mapping of Polyethylene Glycol-modified Alpha-chymotrypsin and Alpha-chymotrypsin: A Comparative Study ,
Biochim Biophys Acta
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Cohen, A.B.
Interaction of Alpha-1-Antitrypsin With Chymotrypsin, Trypsin and Elastase ,
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Cohen, S. , Vaidya, V. and Schultz, R.
Active Site of alpha-Chymotrypsin Activation by Association-Desolvation ,
Proc Natl Acad Sci U S A
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Cohn, M. and Kesslinger, S.
Reversible Inactivation of Chymotrypsin by Sulfate Ions ,
J Biol Chem
 235 , 1365 , 1960
Cruickshank, W.H. and Kaplan, H.
Properties of the Histidine Residues of Indole-Chymotrypsin. Implications for the Activation Process and Catalytic Mechanism ,
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Cuppett, C. and Canady, W.
Thermodynamics of alpha-Chymotrypsin-Substrate and Inhibitor Complex Formation as a Function of pH ,
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 245 , 1069 , 1970
Dahlqvist, U. and Wahlby, S.
Formation of a Covalent Intermediate Between alpha-Chymotrypsin and the B-Chain of Insulin During Enzyme-Catalyzed Hydrolysis ,
Biochim Biophys Acta
 391 , 410 , 1975
Daniels, S.B. and Katzenellenbogen, J.A.
Halo Enol Lactones: Studies on the Mechanism of Inactivation of alpha-Chymotrypsin ,
Biochemistry
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DeCaro, A. , Figarella, C. and Guy, O.
The Two Human Chymotrypsinogens. Purification and Characterization ,
Biochim Biophys Acta
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Delbaere, L. , Hutcheon, W. , James, M. and Thiessen, W.
Tertiary Structural Differences Between Microbial Serine Proteases and Pancreatic Serine Enzymes ,
Nature
 257 , 758 , 1975
Desie, G. , Boens, N. and DeSchryver, F.
Study of Time-Resolved Tryptophan Fluorescence of Crystalline alpha-Chymotrypsin ,
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Desnuelle, P.
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Desnuelle, P. , Gratecos, D. , Harles, M. , Peanasky, R. , Baratti, J. and Rovery, M.
On the Three Chymotrypsinogens of Porcine Pancreas , Structure-Function Relationships of Proteolytic Enzymes , P. Desnuelle, H. Neurath, and M. Ottesen , Academic Press, NY , 21 , 1970
Desnuelle, P. and Rovery, M.
The Proteins of the Exocrine Pancreas ,
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Dijkhof, J. and Poort, C.
A Rapid Method for the Detection of Trypsinogen and Chymotrypsinogen After Electrophoretic Separation of Pancreas Extract on Polyacrylamide Gel ,
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 62 , 598 , 1974
Dorovska-Taran, V. , Momtcheva, R. , Gulubova, N. and Martinek, K.
The Specificity in the Elementary Steps of alpha-Chymotrypsin Catalysis. A Temperature Study with a Series of N-Acetyl-L-Amino Acid Methyl Esters ,
Biochim Biophys Acta
 702 , 37 , 1982
Duda, C.T. and Light, A.
Refolding of Bovine Threonine-Neochymotrypsinogen ,
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Dupaix, A. , Bechet, J. and Roucous, C.
Specificity of alpha-Chymotrypsin. Separation of Polar, Steric, and Specific Effects in the alpha-Chymotrypsin-Catalyzed Hydrolysis of Acyl-Substituted p-Nitrophenyl Esters ,
Biochemistry
 12 , 2559 , 1973
East, E. and Trowbridge, C.
Calorimetric Characterization of Ligand Binding on Trypsinogen and Chymotrypsinogen A with Evidence for Two Binding Sites on alpha-Chymotrypsin ,
J Biol Chem
 248 , 7552 , 1973
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Physiochemical Investigations of the Chymotrypsins I. Demonstration of Heterogeneity of alpha Chymotrypsin by Countercurrent Electrophoresis ,
Arch Biochem Biophys
 66 , 354 , 1957
Eisenberg, M. and Schwert, G.
The Reversible Heat Denaturation of Chymotrypsinogen ,
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 34 , 583 , 1951
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Phenothiazine-N-Carbonyl Chloride, A Specific Inactivator of Chymotrypsin ,
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Sulfonyl Fluorides as Inhibitors of Esterases. I. Rates of Reaction with Acetylcholinesterase, alpha-Chymotrypsin and Trypsin ,
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Fastrez, J. and Fersht, A.
Demonstration of the Acyl-Enzyme Mechanism for the Hydrolysis of Peptides and Anilides by Chymotrypsin ,
Biochemistry
 12 , 2025 , 1973
Fastrez, J. and Fersht, A.
Mechanism of Chymotrypsin. Structure, Reactivity, and Nonproductive Binding Relationships ,
Biochemistry
 12 , 1067 , 1973
Fastrez, J. , Fersht, A. and Blow, D.
Leaving Group Specificity in the Chymotrypsin-Catalyzed Hydrolysis of Peptides. A Stereochemical Interpretation ,
Biochemistry
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Fersht, A. and Renard, M.
pH Dependence of Chymotrypsin Catalysis. Appendix: Substrate Binding to Dimeric alpha-Chymotrypsin Studied by X-ray Diffractin and the Equilibrium Method ,
Biochemistry
 13 , 1416 , 1974
Fersht, A.
The Catalytic Activity of the Inactive Conformation of the alpha-Chymotrypsin ,
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Effect of Dimethyl Sulfoxide on the Interaction of Proflavine with alpha-Chymotrypsin ,
Biochemistry
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Fink, A.
The Isolation of N-Acetyl-L-Tryptophanyl-alpha-Chymotrypsin ,
Arch Biochem Biophys
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Fink, A.
The alpha-Chymotrypsin-Catalyzed Hydrolysis of N-Acetyl-L-Tryptophane p-Nitrophenyl Ester in Dimethyl Sulfoxide at Subzero Temperatures ,
Biochemistry
 12 , 1736 , 1973
Fliss, H. , Tozer, N. and Viswantha, T.
The Reaction of Chymotrypsin with 2,3-Butanedione Trimer ,
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Flohr, K. , Paton, R. and Kaiser, E.
Studies on the Interactions of Spin-Labeled Substrates with Chymotrypsin and with Cycloamyloses ,
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Fojo, A. , Whitney, P. and Awad, W., Jr.
Effects of Acetylation and Guanidination on Alkaline Conformation of Chymotrypsin ,
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Crystal and Molecular Structure of the Bovine a-Chymotrypsin- Eglin-c Complex at 2.0 Angstrom Resolution ,
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Thermodynamics of the Binding of Streptomyces Subtilisin Inhibitor to alpha - Chymotrypsin ,
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Active Site Titration of Immobilized Chymotrypsin with Fluorogenic Reagent ,
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The Trypsin and Chymotrypsin Inhibitory Capacity of Human and Bovine alpha-Crystallin ,
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Mechanism of Inactivation of Chymotrypsin by 3-Benzyl-6-chloro-2-pyrone ,
Biochemistry
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Gerig, J. and Halley, B.
Proton Chemical Shifts in Fluorocinnamate-Chymotrypsin Complexes ,
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Simultaneous Detection of Trypsin and Chymotrypsin and p-Nitroanalide Substrates on Cellulose Acetate Electropherograms ,
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Catalysis by Chymotrypsinogen: Increased Reactivity Due to Oxidation of Methionine 192 ,
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Fluorescence Polarization Studies on the Interaction of Active Site Modified Chymotrypsin in alpha-1-Protease Inhibitor ,
Biochemistry
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Organic Solvent Changes the Chymotrypsin Specificity with Respect to Nucleophiles ,
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Hydrolysis of Nitrophenyl Esters by Proteolytic Enzymes ,
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Proton and Fluorine Nuclear Magnetic Resonance Spectroscopic Observation of Hemiacetal Formation between N-Acyl-p-fluorophenylalaninals and alpha-Chymotrypsin ,
Biochemistry
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Implications of the Chemical Modifications of Chymotrypsin ,
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The Time Dependence of the Activity of alpha-Chymotrypsin at High pH ,
Eur J Biochem
 39 , 293 , 1973
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Steps in the Reactions of Chymotrypsin with Tyrosine Derivatives ,
Biochem J
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Gutfreund, H. and Sturtevant, J.
The Mechanism of the Reaction of Chymotrypsin with p-Nitrophenyl Acetate ,
Biochem J
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Sedimentation Equilibrium Studies of Human Chymotrypsin II and Bovine alpha-Chymotrypsinogen ,
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Organophosphate Inhibitors: The Reactions of Bis(P-Nitrophenyl) Methyl Phosphate with Liver Carboxylesterases and alpha-Chymotrypsin ,
Biochim Biophys Acta
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Active Site Mapping of the Serine Proteases: Human Leukocyte Elastase, Cathepsin G, Porcine Pancreatic Elastase, Rat Mast Cell Proteases I and II, Bovine Chymotrypsin alpha, and Staphylococcus aureus Protease V-8 Using Tripeptide Thiobenzyl Ester Substrates ,
Biochemistry
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Hartley, B. and Massey, V.
The Active Center of Chymotrypsin. 1. Labelling with a Fluorescent Dye ,
Biochim Biophys Acta
 21 , 58 , 1956
Hartley, B.
Amino-acid Sequence of Bovine Chymotrypsinogen A ,
Nature
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Physico-Chemical Characterization of Tryptophyl Residues in Chymotrypsinogen-A and pi-Chymotrypsin ,
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An Electrophoretic Study of Reversible Protein Denaturation: Chymotrypsinogen at High Pressures ,
Biochemistry
 14 , 3257 , 1975
Hawley, S.A.
Electrophoretic Separation of Conformational States of alpha-Chymotrypsinogen A at High Pressures ,
Biochim Biophys Acta
 317 , 236 , 1973
Hedstrom, L. , Moorman, A. , Dobbs, J. and Abeles, R.
Suicide Inactivation of Chymotrypsin by Benzoxazinones ,
Biochemistry
 23 , 1753 , 1984
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Converting Trypsin to Chymotrypsin - the Role of Surface Loops ,
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Raman Spectroscopic Study of the Changes in Secondary Structure of Chymotrypsin: Effect of pH and Pressure on the Salt Bridge ,
Biochim Biophys Acta
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Hill, C. and Tomalin, G.
Kinetic Studies on the Chymotrypsin alpha-Catalyzed Hydrolysis of a Series of N-Acetyl-L-Phenylalanyl Peptides ,
Arch Biochem Biophys
 221 , 324 , 1983
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A Chromatographic Investigation of Chymotrypsinogen alpha ,
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Hoang, D. , Rovery, M. and Desnuelle, P.
Purification and Analysis of Oxidized Chain C of Bovine alpha-Chymotrypsin ,
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Hofstee, B.
Fatty Acid Esters as Substrates for Trypsin and Chymotrypsin ,
Biochim Biophys Acta
 24 , 211 , 1957
Hofstee, B.
Kinetics of Chymotrypsin With a Homologous Series of n-Fatty Acid Esters as Substrates ,
Biochim Biophys Acta
 32 , 182 , 1959
Horbett, T. and Teller, D.
Low pH Dimerization Behavior of Active Site Derivatives of Bovine alpha-Chymotrypsin ,
Biochemistry
 12 , 1349 , 1973
Howell, J. , Beck, T. , Bates, B. and Hunter, M.
Interaction of alpha-2-Macroglobulin with Trypsin, Chymotrypsin, Plasmin and Papain ,
Arch Biochem Biophys
 221 , 261 , 1983
Hummel, B.
A Modified Spectrophotometric Determination of Chymotrypsin, Trypsin and Thrombin ,
Can J Biochem Physiol
 37 , 1393 , 1959
Hunt, A.H. and Jirgensons, B.
Effect of Sodium Dodcyl Sulfate and Its Homologs on Circular Dichroism of alpha-Chymotrypsin ,
Biochemistry
 12 , 4435 , 1973
Iio-Akama, K. , Sasamoto, H. , Miyazawa, K. , Miura, S. and Tobita, T.
Active Forms of Chymotrypsin C Isolated from Autolyzed Porcine Pancreas Glands ,
Biochim Biophys Acta
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Imperiali, B. and Abeles, R.
Extended Binding Inhibitors of Chymotrypsin That Interact with Leaving Group Subsites S1'-S3' ,
Biochem J
 26 , 4474 , 1987
Imperiali, B. and Abeles, R.
Inhibition of Serine Proteases of Peptidyl Fluoromethyl Ketones ,
Biochemistry
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Nonspecific Catalyses by alpha-Chymotrypsin and Trypsin ,
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Digestibility of the Active Fragment of Potato Proteinase Inhibitor IIa by Bovine Chymotrypsin and a Bacterial Proteinase ,
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The alpha-Chymotrypsin-Catalyzed Hydrolysis of Sepharose-Bound L-Phenylalanine 4-Nitroanilide ,
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Inhibition of the Proteinase and Esterase Activities of Trypsin and Chymotrypsin by Diisopropyl Fluorophosphate: Crystallization of Inhibited Chymotrypsin ,
J Biol Chem
 179 , 189 , 1949
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The Binding of Inhibitors to alpha-Chymotrypsin ,
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Inhibition of alpha-Chymotrypsin by Hydroxymethyl Analogues of D- and L- N-Acetylphenylalanine and N-Acetyltryptophan of Potential Affinity Labelling Value ,
Biochim Biophys Acta
 341 , 184 , 1974
Kassell, B. and Laskowski, M.
A Comparison of the Terminal Amino Acids of Chymotrypsinogen B and alpha Chymotrypsinogen ,
J Biol Chem
 237 , 413 , 1962
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The Specific Peptidase and Esterase Activities of Chymotrypsin ,
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Remodeled Enzyme. 1. Characteristics of Chymotrypsin Modified with Water-Soluble Acylating Reagents and Its Peptide Synthesis Ability in Aqueous Organic Media ,
Biosci Biotechnol Biochem
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Exponential Function of Chymotrpsin Action ,
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The Proteins of Bovine Pancreatic Juice ,
J Biol Chem
 233 , 344 , 1958
Kerr, M. , Walsh, K. and Neurath, H.
Catalysis by Serine Proteases and Their Zymogens. A Study of Acyl Intermediates by Circular Dichroism ,
Biochemistry
 14 , 5088 , 1975
Kezdy, F. and Bender, M.
The Observation of Acyl-Enzyme Intermediates in the alpha-Chymotrypsin-Catalyzed Hydrolysis of Specific Ester Substrates at Low pH ,
J Am Chem Soc
 86 , 937 , 1964
Klayman, M. , Massey, B. , Pleticka, S. , Galambos, J. , Brandborg, L. , Kirsner, J. and Palmer, W.
The Cytologic Diagnosis of Gastric Cancer by Chymotrypsin Lavage ,
Gastroenterology
 29 , 849 , 1955
Klayman, M. , Massey, B, Pleticka, S. , Galambos, J. , Brandborg, L. , Kirsner, J. and Palmer, W.
The Cytologic Diagnosis of Gastric Cancr of Chymotrypsin Lavage. II. The Detection of Early Malignancy ,
Gastroenterology
 29 , 854 , 1955
Klyosov, A. , VanViet, N. and Berezin, I.
The Reactions of alpha-Chymotrypsin and Related Proteins with Ester Substrates in Non-Aqueous Solvents ,
Eur J Biochem
 59 , 3 , 1975
Kogan, R. and Fife, T.
Electronic Effects in the Acylation of alpha-Chymotrypsin by Substituted N-Benzoylimidazoles ,
Biochemistry
 23 , 2983 , 1984
Kogan, R. and Fife, T.
Influence of Hydrophobic and Steric Effects in the Acyl Group on Acylation of alpha-Chymotrypsin by N-Acylimidazoles ,
Biochemistry
 24 , 2610 , 1985
Koida, A. and Matsuoka, Y.
Studies on Fin Whale Pancreatic Proteases. III. Properties of Purified Fin Whale Anionic Chymotrypsin ,
J. Biochem.
 68 , 1 , 1970
Kostka, V. and Carpenter, F.
Inhibition of Chymotrypsin Activity in Crystalline Trypsin Preparations ,
J Biol Chem
 239 , 1799 , 1964
Kullmann, W.
Kinetics of Chymotrypsin- and Papain-catalyzed Synthesis of [Leucine]enkephalin and [Methionine]enkephalin ,
Biochem J
 220 , 405 , 1984
Kumar, S. and Hein, G.
A Rapid Kinetic Assay Method for alpha-Chymotrypsin and Its Applications ,
Anal Biochem
 30 , 203 , 1969
Kumar, S. and Hein, G.
Concerning the Mechanism of Autolysis of alpha-Chymotrypsin ,
Biochemistry
 9 , 291 , 1970
Kumar, S. and Hein, G.
Structural and Steric Specificity of alpha-Chloroketones as Inhibitors of alpha-Chymotrypsin ,
Biochim Biophys Acta
 206 , 404 , 1970
Kunitz, M. and Northrop, J.
Crystalline Chymotrypsin and Chymotrypsinogen. Isolation, Crystallization and General Properties of a New Proteolytic Enzyme and Its Precursor ,
J Gen Physiol
 18 , 433 , 1935
Kunitz, M.
Crystallization of Salt-Free Chymotrypsinogen and Chymotrypsin from Solution in Dilute Ethyl Alcohol ,
J Gen Physiol
 32 , 265 , 1948
Kunitz, M.
Formation of New Crystalline Enzymes from Chymotrypsin, Isolation of beta and gamma Chymotrypsin ,
J Gen Physiol
 32 , 207 , 1938
Kurtz, A. and Niemann, C.
Nitrogen Analogs of Representative Substrates and Inhibitors of alpha-Chymotrypsin ,
Biochim Biophys Acta
 50 , 520 , 1961
Lagunoff, D. , Chi, E. and Wan, H.
Effects of Chymotrypsin and Trypsin on Rat Peritoneal Mast Cells ,
Biochem Pharmacol
 24 , 1573 , 1975
Lazdunski, M. , Delaage, M. , Abita, J. and Vincent, J.
The Role of Carboxylates and Phenol Side-Chains in the Activity and Conformation of Trypsinogen, Trypsin, Chymotrypsinogen and Chymotrypsin , Structure-Function Relationships of Proteolytic Enzymes , P. Desnuelle, H. Neurath, and M. Ottesen , Academic Press, NY , 42 , 1970
Maehler, R. and Whitaker, J.
Dynamics of Ligand Binding to alpha-Chymotrypsin and to N-Methyl-alpha-Chymotrypsin ,
Biochemistry
 21 , 4621 , 1982
Maguire, R. , Hijazi, N. and Laidler, K.
Transient-Phase Kinetics of alpha-Chymotrypsin and Other Enzyme Systems ,
Biochim Biophys Acta
 341 , 1 , 1974
Marini, M. and Hess, G.
The alpha Chymotrypsin Catalyzed Hydrolysis of p-Nitrophenyl Acetate ,
J Am Chem Soc
 82 , 5160 , 1960
Martin, B. and Viswanatha, T.
Selective Reduction of a Disulfide Bond in Chymotrypsin A ,
Biochem Biophys Res Commun
 63 , 247 , 1975
Martin, C. , Golubow, J. and Axelrod, A.
A Rapid and Sensitive Spectrophotometric Method for the Assay of Chymotrypsin ,
J Biol Chem
 234 , 294 , 1959
Martin, C. , Golubow, J. and Axelrod, A.
The Hydrolysis of Carbobenzoxy-L-tyrosine p-Nitrophenyl Ester by Various Enzymes ,
J Biol Chem
 234 , 1718 , 1959
Matta, M. and Staley, D.
Specificities of alpha-Chymotrypsin and Subtilisin Carlsberg. The Acylamido Effect in beta-Phenylpropionates and Their Rigid Analogs ,
J Biol Chem
 249 , 732 , 1974
Mavridis, A. , Tulinsky, A. and Liebman, M.
Asymmetrical Changes in Tertiary Structure of alpha-Chymotrypsin with Change in pH ,
Biochemistry
 13 , 3661 , 1974
McLachlan, A.
Gene Duplication in the Structural Evolution of Chymotrypsin ,
J Mol Biol
 128 , 48 , 1979
Meister, A. , Weinrich, S. , Nelson, C. and Rutter, W.
The Chymotrypsin Enhancer Core. Specific Factor Binding and Biological Activity ,
J Biol Chem
 264 , 20744 , 1989
Meloun, B. , Kluh, I. , Kostka, V. , Moravek, L. , Prusik, Z. , Vanecek, J. , Keil, B. and Sorm, F.
Covalent Structure of Bovine Chymotrypsinogen A ,
Biochim Biophys Acta
 130 , 543 , 1966
Miller, D. D. , Horbett, T. and Teller, D.
Reevaluation of the Activation of Bovine Chymotrypsinogen A ,
Biochemistry
 10 , 4641 , 1971
Mishra, A. and Klapper, M.
Permeable Membrane/Mass Spectrometric Measurement of Solvent 1H2H, 12C13C, and 16O18O Kinetic Isotope Effects Associated with alpha-Chymotrypsin Deacylation: Evidence for Reaction Mechanism Plasticity ,
Biochemistry
 25 , 7328 , 1986
Monsees, T. , Geiger, R. and Miska, W.
A Novel Bioluminogenic Assay for a-Chymotrypsin ,
J Biolumin Chemilumin
 10 , 213 , 1995
Moore, W.
Behavior of Chymotrypsinogen During Low pH Gel Electrophoresis Is Altered by Persulfate ,
Biochim Biophys Acta
 870 , 372 , 1986
Morii, M. and Travis, J.
Amino Acid Sequence at the Reactive Site of Human alpha-1-Antichymotrypsin ,
J Biol Chem
 258 , 12749 , 1983
Mozhaev, V. , Meliknubarov, N. , Levitsky, V. , Siksnis, V. and Martinek, K.
High Stability to Irreversible Inactivation at Elevated Temperatures of Enzymes Covalently Modified by Hydrophilic Reagents - alpha-Chymotrypsin ,
Biotechnol Bioeng
 40 , 650 , 1992
Mozhaev, V. , Sergeeva, M. , Belova, A. and Khmelnitsky, Y.
Multipoint Attachment to a Support Protects Enzyme from Inactivation by Organic Solvents: alpha-Chymotrypsin in Aqueous Solutions of Alcohols and Diols ,
Biotechnol Bioeng
 35 , 653 , 1990
Mozhaev, V. , Siksnis, V. , Melik-Nubarov, N. , Galkantaite, Z. , Denis, G. , Butkus, E. , Yaslavsky, B. , Mestechkina, N. and Martinek, K.
Protein Stabilization via Hydrophilization - Covalent Modification of Trypsin and alpha-Chymotrypsin ,
Eur J Biochem
 173 , 147 , 1988
Mullen, G. , Dunlap, R. and Odom, J.
Synthesis and Characterization of a Selenium-Containing Substrate of alpha-Chymotrypsin. Selenium-77 Nuclear Magnetic Resonance Observation of an Acyl-alpha-Chymotrypsin Intermediate ,
Biochemistry
 25 , 5625 , 1986
Neiderau, C. , Grendell, J. and Rothman, S.
Digestive End Products Release Pancreatic Enzymes from Particulate Cellular Pools, Particularly Zymogen Granules ,
Biochim Biophys Acta
 881 , 281 , 1986
Neil, G. , Niemann, C. and Hein, G.
Structural Specificity of alpha-Chymotrypsin: Polypeptide Substrates ,
Nature
 210 , 903 , 1966
Neimann, C.
alpha-Chymotrypsin and the Nature of Enzyme Catalysis ,
Science
 143 , 1287 , 1964
Neurath, H. and Dixon, G.
Structure and Activation of Trypsinogen and Chymotrypsinogen ,
Fed Proc
 16 , 791 , 1957
Northrop, J. , Kunitz, M. and Herriott, R.
, Crystalline Enzymes, 2nd ed , Columbia Univ Press, NY , 96 , 1948
Orsinih, G. , Skrzynia, C. and Goldberg, M.
The Renaturation of Reduced Polyalanyl-Chymotrypsinogen and Chymotrypsinogen ,
Eur J Biochem
 59 , 433 , 1975
Osborne, W. and Tashian, R.
The Proteolytic Degradation of Normal and Variant Human Carbonic Anhydrase Isozymes by alpha-Chymotrypsin ,
J Biol Chem
 256 , 1330 , 1981
Paberit, M.
Kinetic Salting Effect as a Promising Tool in the Investigation of Enzyme Molecule Changes upon Reaction:Deacylation of Acyl-Chymotrypsins ,
Bioorg Chem
 18 , 228 , 1990
Pandit, N. and Rao, M.
Studies on Self-Association of Proteins. The Self-Association of alpha-Chymotrypsin at pH 8.3 and Ionic Strength 0.05 ,
Biochemistry
 13 , 1048 , 1974
Parisi, M. and Abeles, R.
Inhibition of Chymotrypsin by Fluorinated alpha-Keto Acid Derivatives ,
Biochemistry
 31 , 9429 , 1992
Peanasky, R. , Bentz, Y. , Homandberg, G. , Minor, S. and Babin, K.
The Isoinhibitors of Chymotrypsin/Elastase from Acaris lumbricoides: The Reactive Site ,
Arch Biochem Biophys
 232 , 135 , 1984
Peanasky, R. , Bentz, Y. , Paulson, B. , Graham, D. and Babin, K.
The Isoinhibitors of Chymotrypsin/Elastase from Ascaris lumbricoides: Isolation by Affinity Chromatography and Association with the Enzymes ,
Arch Biochem Biophys
 232 , 127 , 1984
Phillips, R. , Matthews, M. , Olson, E. and Von Tersch, R.
Structural and Sterochemical Studies of Esterification of Aromatic Amino Acids by alpha-Chymotrypsin in Alcohol Solvents ,
Enzyme Microb Technol
 12 , 31 , 1990
Ponzi, D. and Hein, G.
Stereospecific Activation of Chymotrypsin Catalyzed Hydrolyses ,
Biochem Biophys Res Commun
 25 , 60 , 1966
Powers, F. and Carroll, D.
Reaction of Acyl Carbazates with Proteolytic Enzymes ,
Biochem Biophys Res Commun
 67 , 639 , 1975
Powers, J. , Tanaka, T. , Harper, J. , Minematsu, Y. , Barker, L. , Lincold, D. , Crumley, K. , Fraki, J. , Schechter, N. , Lazarus, G. , Nakajima, K. , Nakashino, K. , Neurath, H. and Wodbury, R.
Mammalian Chymotrypsin-like Enzymes. Comparative Reactivities of Rat Mast Cell Proteases, Human and Dog Skin Chymases and Human Cathepsin G with Peptide Chloromethyl Ketone and Sulfonyl Fluoride Inhibitors ,
Biochemistry
 24 , 2048 , 1985
Purdie, J. and Benoiton, N.
The Interaction of alpha-Chymotrypsin with Phenylalanine Derivatives Containing a Free alpha-Amino Group ,
Can J Biochem
 48 , 1058 , 1970
Ramakrishna, T. and Pandit, M.
Involvement of Active Site in Self-Association of Proteins - A Case of alpha-Chymotrypsin ,
Indian J Biochem Biophys
 29 , 192 , 1992
Rao, K. and Lombardi, B.
Substrate Solubilization for the Hummel alpha-Chymotrypsin Assay ,
Anal Biochem
 65 , 548 , 1975
Rao, M. and Kegeles, G.
An Ultracentrifuge Study of the Polymerization of alpha-Chymotrypsin ,
J Am Chem Soc
 80 , 5724 , 1958
Rawn, J. and Lienhard, G.
The Binding of Boronic Acids to Chymotrypsin. [Correction: 13, 5452 (1974)] ,
Biochemistry
 13 , 3124 , 1974
Ray, W. , Latham, H. , Katsoulis, M. and Koshland, D.
Evidence for Involvement of a Methionine Residue in the Enzymatic Action of Phosphoglucomutase and Chymotrypsin ,
J Am Chem Soc
 82 , 4743 , 1960
Remy, M. , Bacou, P. , Bourdillon, C. and Thomas, D.
Kinetics of Amino Acid Esterification Catalyzed by Hydrophobic Derivatives of alpha-Chymotrypsin ,
Biochim Biophys Acta
 911 , 252 , 1987
Riechmann, L. and Kasch, V.
Peptide Synthesis Catalyzed by the Serine Proteinases Chymotrypsin and Trypsin ,
Biochim Biophys Acta
 830 , 164 , 1985
Rinderknecht, H. and Fleming, R.
A New Highly Sensitive and Specific Assay for Chymotrypsin ,
Clin Chim Acta
 59 , 139 , 1975
Ringe, D. , Mottonen, J. , Gelb, M. and Abeles, R.
X-Ray Diffraction Analysis of the Inactivation of Chymotrypsin by 3-Benzyl-6-chloro-2-pyrone ,
Biochemistry
 25 , 5633 , 1986
Ringe, D. , Seaton, B. , Gelb, M. and Abeles, R.
Inactivation of Chymotrypsin by 5-Benzyl-6-chloro-2-pyrone: 13C NMR and X-Ray Diffraction Analyses of the Inactivator-Enzyme Complex ,
Biochemistry
 24 , 64 , 1985
Ritonja, A. , Meloun, B. and Gubensek, F.
The Primary Structure of Vipera ammodytes Venom Trypsin Inhibitor ,
Biochim Biophys Acta
 748 , 429 , 1983
Rubin, C. and Benditt, E.
A Simplified Technique Using Chymotrypsin Lavage for the Cytological Diagnosis of Gastric Cancer ,
Cancer
 8 , 1137 , 1955
Rumsh, L. , Volkova, L. and Antonov, V.
Hydrolysis of L-3-Benzyl-2,5-Diketomorpholine by Chymotrypsin ,
F.E.B.S. Lett.
 9 , 64 , 1970
Ryan, C. and Balls, A.
An Inhibitor of Chymotrypsin from Solanum tuberosum and Its Behavior Towards Trypsin ,
Proc Natl Acad Sci U S A
 48 , 1839 , 1962
Sanders, M. , Walsh, K. and Arnon, R.
Immunological Cross-Reaction Between Trypsin and Chymotrypsin as a Guide to Structural Homology ,
Biochemistry
 9 , 2356 , 1970
Sasaki, T. and Itou, H.
Interactions of Silkworm Antichymotrypsin with alpha-Chymotrypsin, Trypsin, Subtilisin BPN' and Two Silkworm Alkaline Proteinases ,
Biochim Biophys Acta
 831 , 151 , 1985
Sato, E. , Sakashita, M. , Kanaoka, Y. and Kosower, E.
Organic Fluorescent Reagents . XIV. Novel Fluorogenic Substrates for Microdetermination of Chymotrypsin and Aminopeptidase: Bimane Fluorescence Appears after Hydrolysis ,
Bioorg Chem
 16 , 298 , 1988
Sawyer, C. and Kirsch, J.
Kinetic Isotope Effects for the Chymotrypsin Catalyzed Hydrolysis of Ethoxyl-118O Labelled Specific Ester Substrates ,
J Am Chem Soc
 97 , 1963 , 1975
Schechler, N. , Fraki, J. , Geesin, J. and Lazaurus, G.
Human Skin Chymotryptic Proteinase. Isolation and Relation to Cathepsin G and Rat Mast Cell Proteinase I ,
J Biol Chem
 258 , 2973 , 1983
Schellenberger, V. and Jakubke, H.
A Spectrophotometric Assay for the Characterization of the S1Subsite Specificity of alpha-Chymotrypsin ,
Biochim Biophys Acta
 869 , 54 , 1986
Schellenberger, V. , Braune, K. , Hofmann, H. and Jakubke, H.
The Specificity of Chymotrypsin - A Statistical Analysis of Hydrolysis Data ,
Eur J Biochem
 199 , 623 , 1991
Schellenberger, V. , Schellenberger, U. , Mitin, Y. and Jakubke, H.
Charcterization of the S1-Subsite Specificity of Bovine Pancreatic alpha-Chymotrypsin Via Acyl Transfer to Added Nucleophiles ,
Eur J Biochem
 187 , 163 , 1990
Schoellmann, G. and Shaw, E.
Direct Evidence for the Presence of Histidine in the Active Center of Chymotrypsin ,
Biochemistry
 2 , 252 , 1963
Schricker, B. , Thirring, K. and Berner, H.
alpha-Chymotrypsin Catalyzed Enantioselective Hydrolysis of Alkenyl-alpha-Amino Acid Esters ,
Bioorg Med Chem
 2 , 387 , 1992
Schultz, R. and Cheerva, A.
The Binding of a Non-Specific Transition State Analogue to alpha-Chymotrypsin ,
F.E.B.S. Lett.
 50 , 47 , 1975
Schultz, R. , Konovessi-Panayotatos, A. and Treadway, W., Jr.
The Existence of Muliple Conformational Forms in Anhydrochymotrypsin ,
Biochem Biophys Res Commun
 60 , 535 , 1974
Schwert, G. and Kaufman, S.
The Substrate Specificity and Sedimentation Behavior of gamma-Chymotrypsin ,
J Biol Chem
 180 , 517 , 1949
Schwert, G. and Takenaka, Y.
A Spectrophotometric Determination of Trypsin and Chymotrypsin ,
Biochim Biophys Acta
 16 , 570 , 1955
Schwert, G.
The Molecular Size and Shape of the Pancreatic Proteases. I. Sedimentation Studies on Chymotrypsinogen and on alpha and gamma Chymotrypsin ,
J Biol Chem
 179 , 655 , 1949
Serralheiro, M. , Empis, J. and Cabral, J.
Thermostability of alpha-Chymotrypsin Encapsulated in Reverse Micelles ,
Biotechnol Prog
 12 , 167 , 1990
Shah, D. and Gorenstein, D.
Fluorine Nuclear Magnetic Resonance Spectroscopy of "Transition State Analogue" Complexes of the D and L Enantiomers of N-Acetyl-p-Fluorophenylalaninal and alpha-Chymotrypsin ,
Biochemistry
 22 , 6096 , 1983
Shalitan, Y. and Brown, J.
Isolation of a Specific Acyl-Chymotrypsin Intermediate ,
Biochem Biophys Res Commun
 24 , 817 , 1966
Sharma, S. and Hopkins, T.
Acylation of the Alanine149 N-Terminal of alpha-Chymotrypsin and Its Effect on Catalytic Function ,
Biochim Biophys Acta
 701 , 413 , 1982
Shaw, E. , Mares-Guia, M. and Cohen, W.
Evidence for an Active-Center Histidine in Trypsin through Use of a Specific Reagent, 1-Chloro-3-tosylamido-7-amino-2-heptanone, the Chloromethyl Ketone Derived from Na -Tosyl-L-lysine ,
Biochemistry
 4 , 2219 , 1965
Shaw, M. , Kay, T. and Viswanatha, T.
The Activation of Chymotrypsinogen by Papain ,
Can J Biochem
 48 , 1208 , 1970
Shearwin, K. and Winzor, D.
Effect of Calcium Ion on the Dimerization of alpha-Chymotrypsin ,
Biochim Biophys Acta
 1038 , 136 , 1990
Shih, Y. , Prausnitz, J. and Blanch, H.
Some Characteristics of Protein Precipitation by Salts ,
Biotechnol Bioeng
 40 , 1155 , 1992
Smilie, L. and Hartley, B.
Histidine Sequences in the Active Centres of Some Serine Proteinases ,
Biochem J
 101 , 232 , 1966
Smith, E. , Brown, D. and Laskowski, M.
Molecular Weight of Chymotrypsinogen and Chymotrypsin alpha and beta ,
J Biol Chem
 191 , 639 , 1951
Spencer, P. , Titus, J. and Spencer, R.
Direct Fluorimetric Assay for Proteolytic Activity Against Intact Proteins ,
Anal Biochem
 64 , 556 , 1975
Stein R. and Strimpler, A.
Slow-Binding Inhibition of Chymotrypsin and Cathepsin G by the Peptide Aldehyde Chymostatin ,
Biochemistry
 26 , 2611 , 1987
Svensson, K. , Imhoff, J. and Keil, B.
Enzymic Properties of Nitrated alpha-Chymotrypsin and delta-Chymotrypsin ,
Eur J Biochem
 58 , 493 , 1975
Tanizawa, K. and Bender, M.
The Application of Insolubilized alpha-Chymotrypsin to Kinetic Studies on the Effect of Aprotic Dipolar Organic Solvents ,
J Biol Chem
 249 , 2130 , 1974
Tian, W. and Tsou, C.
Determination of Rate Constant of Enzyme Modification by Measuring the Substrate Reaction in the Presence of the Modifier ,
Biochemistry
 21 , 1028 , 1982
Tung, M. and Steiner, R.
The Self-Association of Chymotrypsinogen A ,
Eur J Biochem
 44 , 49 , 1974
Turbeck, B. and Graae, J.
The Combined Effect of Thiocyanate Ions and Rise in Temperature on the Action of alpha-Chymotrypsin on Tyrosine Ethyl Ester ,
Acta Chem Scand
 23 , 2414 , 1969
Turner, R. , Liener, I. and Lovrien, R.
Equilibria of Bowman-Birk Inhibitor Association with Trypsin and Chymotrypsin ,
Biochemistry
 14 , 275 , 1975
Valenzuela, P. and Bender, M.
Binding of Competitive Inhibitors of delta-Chymotrypsin in the Alkaline pH Region. Competitive Inhibition Kinetics and Proton-Uptake Measurements ,
Biochemistry
 9 , 2440 , 1970
Weber, B. , Storm, M. and Boyer, P.
An Assessment of the Exchangeability of Water Molecules in the Interior of Chymotrypsinogen in Solution ,
Arch Biochem Biophys
 163 , 1 , 1974
Weber, J. , Turpin, P. , Bernhard, S. and Peticolas, W.
Chromophoric Cinnamic Acid Substrates as Resonance Raman Probes of the Active Site Environment in Native and Unfolded alpha-Chymotrypsin ,
Biochemistry
 25 , 1912 , 1986
Wedler, F. , Uretsky, L. and McClune, G.
Conformational States of Chymotrypsin at High pH: Substrate Activation and Sidechain Interactions ,
Biochim Biophys Acta
 370 , 541 , 1974
Wedler, F. , Uretsky, L. , McClune, G. and Cencula, J.
Conformational States of Chymotrypsin at High pH: Temperature Effects on Catalysis and Binding ,
Arch Biochem Biophys
 170 , 476 , 1975
Weidmann, B. and Abeles, R.
Mechanism of Inactivation of Chymotrypsin by 5-Butyl-3H-1,3-oxazine-2.6-dione ,
Biochemistry
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Wells, G. , Mustafi, D. and Makinen, M.
Structure at the Active Site of an Acylenzyme of alpha-Chymotrypsin and Implications for the Catalytic Mechanism ,
J Biol Chem
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Westheimer, F.
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Active Site Directed Inhibition of Enzymes Utilizing Deaminatively Produced Carbonium Ions. Applications to Chymotrypsin ,
J Am Chem Soc
 97 , 2290 , 1976
Wilcox, P. , Kraut, J. , Wade, R. and Neurath, H.
The Molecular Weight of alpha-Chymotrypsinogen ,
Biochim Biophys Acta
 24 , 72 , 1957
Wilcox, P.
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Wu, A. , Eitenmiller, R. and Powers, J.
Yields from Chymotrypsin and Lysozyme under Fluctuating Temperature Treatments ,
J Food Sci
 40 , 840 , 1975
Wu, F. and Laskowski, M.
The Effect of Calcium on Chymotrypsin alpha and beta ,
Biochim Biophys Acta
 19 , 110 , 1956
Yamashita, M. , Arai, S. , Tanimoto, S. and Fujimaki, M.
Mode of Action of alpha-Chymotrypsin in Its Reverse Reaction at pH 5.3 ,
Biochim Biophys Acta
 358 , 105 , 1974
Yamashita, T.
Action of Chymotrypsin on Synthetic Substrates. V. Action of alpha-Chymotrypsin on Glycyl-L-aminoacyl-L-tyrosinamides ,
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 48 , 846 , 1960
Yapel, A. , Han, M. , Lumry, R. , Rosenberg, A. and Shiao, D.
Studies of the Chymotrypsinogen Family. V. The Effect of Small-Molecule Contaminants on the Kinetic Behavior of alpha-Chymotrypsin ,
J Am Chem Soc
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Zeeberg, B. and Caplow, M.
Transition State Charge Distribution in Reactions of an Acetyltyrosylchymotrypsin Intermediate ,
J Biol Chem
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Zeeberg, B. , Caplow, M. and Caswell, M.
Substrate Induced pK Perturbations with Chymotrypsin and the Possible Significance of Non-productive Binding ,
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Enantioselective and Reversible Inhibition of Trypsin and alpha-Chymotrypsin by Phosphonate Esters ,
Biochemistry
 33 , 8128 , 1994

Chymotrypsin Products

Description
Activity
Code
Cat. #
Size
Price
Description
Chymotrypsin, Alpha, TLCK Treated, Sequencing Grade
Source:
Bovine Pancreas
Three time crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219 (1965)]. Dialyzed to remove autolysis products and low molecular weight contaminants. Supplied as lyophilized powder.
Store at 2-8°C.
…
Activity
≥40 u/mgP
Code
CDSEQ
LS02130
4x25 ug
$188.00
LS02132
4x100 ug
$490.00
Description
Chymotrypsin, Alpha, TLCK Treated
Source:
Bovine Pancreas
Three times crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219 (1965)]. Dialyzed against 1 mM HCl to remove autolysis products and low molecular weight contaminants. Supplied as a dialyzed, lyophilized powder.
Store at 2-8°C.
…
Activity
≥45 units per mg protein
Code
CDTLCK
LS001430
25 mg
$33.00
LS001432
100 mg
$80.00
LS001434
1 gm
$620.00
LS001438
Bulk
---
The minimum amount for bulk packaging/pricing for this product is 20000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
Description
Chymotrypsin, Alpha, Purified
Source:
Bovine Pancreas
Chromatographically prepared by the procedure of Yapel, et al., J. Amer. Chem. Soc., 88, 2573 (1966). A lyophilized powder.
Store at 2-8°C.
…
Activity
≥45 units per mg protein
Code
CDS
LS001475
100 mg
$79.00
LS001479
1 gm
$605.00
LS001477
Bulk
---
The minimum amount for bulk packaging/pricing for this product is 20000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
Description
Chymotrypsin, Alpha
Source:
Bovine Pancreas
Three times crystallized alpha chymotrypsin which is an activation product of a 3X crystallized zymogen. Dialyzed against 1mM HCl and lyophilized.
Store at 2-8°C.
…
Activity
≥45 units per mg protein
Code
CDI
LS001448
250 mg
$46.00
LS001450
1 gm
$133.00
LS001451
10 gm
$995.00
LS001453
Bulk
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The minimum amount for bulk packaging/pricing for this product is 200000 x 1 mg. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
Description
Chymotrypsin, Alpha
Source:
Bovine Pancreas
Crystallized as zymogen and activated. Dialyzed against 1mM HCl and lyophilized.
Store at 2-8°C.
…
Activity
≥35 units per mg protein
Code
CDAG
LS001333
1 gm
$40.00
LS001334
10 gm
$235.00
LS001332
Bulk
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The minimum amount for bulk packaging/pricing for this product is 200 x 1 gm. Please contact custservice@worthington-biochem.com to request a quote for smaller amounts.
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